Fertility treatments – Blastocyst transfer:
Blastocyst transfer is an important technique that has been developed for In vitro fertilization. This procedure aims to maximize the pregnancy rates and minimizing the risk of multiple births.
A blastocyst is an embryo that has been developed or grows in the laboratory and undergoes developmental changes for six days after insemination before being given back to the womb.
Maximizing the pregnancy rates:
This allows the embryologist to choose more advanced embryos with well potential for implantation at the time of the transfer to your womb and ultimate pregnancy. This reduces the occurrence of possibly risk of multiple births.
The method is very effective with patients who are younger & have a large number of eggs presented at retrieval. On average, patients with six or more high quality embryos on day three are the best entrants for blastocyst culture because there is a healthier chance of more embryos developing effectively to day five. Embryos developing to the critical blastocyst stage have a much greater chance of inserting successfully and resulting in constant pregnancy.
Consequently, if in vitro culture environments are maximized so healthy blastocysts form at a high rate, and then day 5 blastocyst embryo transfer can be done.
In couples who have experienced continual disappointments of implantation, a different technique would be to culture the embryos up to the 5th day when they become blastocysts. In a natural cycle, this is the stage when the embryo truly implants in the uterus. Blastocyst culture copycats the natural cycle, thereby increasing the probabilities of pregnancy.
Advantages of blastocyst culture:-
- Better selection of the embryos to be transferred
- Limit the number of embryos to be transferred
- Eliminate the risk of multiple pregnancies, better implantation rate.
Why is blastocyst culture so successful?
Blastocyst culture uses a selection pressure on a collection of embryos and only the strongest and rightest will mature effectively to the blastocyst stage. Blastocyst culture will increase the probability of transferring a genetically normal embryo with a high implantation potential.